^{Seasonal First Impressions is a column where I detail my thoughts, however brief or long, about a currently-airing anime’s first episode or so.}

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A sickness called the Rust. Forbidden mushrooms that offer toxic euphoria. A desert with iron sand and the foggy streets of the sin city beyond it. Those streets crawl with the sick and dying, hucksters, hookers, butchers, and a doctor with a heart of gold. This is Sabikui Bisco, one of the season’s most singular offerings.

Bisco is absolutely suffused with atmosphere, and it’s tempting to spend the entire article talking about that instead of the actual story (which is only in its very early stages anyway.) But we should at least touch on that before we get into what this thing is actually about. Despite a fairly modest production from an animation point of view, the visuals on this thing are beyond engrossing. (The series comes to us from the brand-new studio OZ. This is, as far as I can tell, their first-ever production.) Almost everything in the city itself is lit with a neon undertone that really sells the whole “Las Vegas of post-apoc Japan” vibe. The character designs, similarly, really pop, and there’s a lot to love about them. Even minor characters get to look good.

But yes, about that “post-apoc Japan” bit. Bisco takes place in a world overrun with something called The Rusty Wind. It makes people sick, and eventually kills them. Also factoring in are a group of people who have some sort of supernatural control over those mushrooms I mentioned before, The Mushroomkeepers. I am quite sure that before watching this episode I had never heard the phrase “mushroom terrorist” in my entire life. Having now seen it, I’ve heard it several times. Most people don’t seem to like the Mushroomkeepers, and while it’s too early to draw clean good guy / bad guy lines (if that’s something this series ever wants to do at all), it’s not hard to get why. Most Mushroomkeeper activity seems to consist of causing huge colonies of tree-sized caps to sprout in places, which causes a lot of damage. One of our protagonists, the titular Bisco (that’s the wild-eyed redhead on the cover. Played here by Ryouta Suzuki, probably best known to readers here as Ishigami from Kaguya-sama: Love is War!) is a Mushroomkeeper. Apparently quite an infamous one. We’re made aware of his legend in this utterly brilliant exchange from the episode’s opening minutes.

Bisco himself doesn’t do a ton in this first episode. What he does do is quite impactful and sets the whole plot in motion, but we’ll circle back around to that. Let’s talk about our other protagonist first.

Milo “Panda” Nekoyanagi (Natsuki Hanae, easily best known as the lead, Tanjirou, in Demon Slayer) is a feminine-looking doctor with a heart of gold who appears to quite literally treat his patients out of a brothel. He seems like a genuinely very nice man, as demonstrated by his habit of giving away treatment (both for Rust and a number of other things) for free. He also collects illegal mushrooms, hoping to synthesize a permanent cure for the disease from them. There’s a personal investment here, as his sister Paw, the city’s guard captain (Reina Kondou, who given that she was also Nikaido in the Dorohedoro anime, seems to be building a niche for herself voicing dangerous women in weird science fantasy settings) is also ill with the disease.

Milo also has one other connection we should discuss. That with the prefectural governor, Kurokawa. (Kenjirou Tsuda, an industry veteran most famous as Seto Kaiba from Yu-Gi-Oh! Though I’d be remiss to not also mention his roles as The Giraffe from Revue Starlight and the talking dog Yamabiko from Sonny Boy.) Kurokawa does not seem to be a nice man, and in his first on-screen appearance tries to bully Milo into abandoning his sister so he can offer his services to the prefecture’s rich elite instead.

His attempt at a verbal beatdown is interrupted, though, by Bisco, who for reasons currently unknown to us, lets loose a mushroom colony in the middle of the city. Utter chaos ensues, with Paw dawning her guard uniform to go stop him despite Milo’s pleas. (And if I may, she looks amazing while doing it, too.)

^{I try to keep obvious thirsting over anime girls to a minimum on this site, but you’ll have to pardon me here, I have a type.}

Paw actually knocks Milo out, but, unfazed, the good doctor simply slinks into his laboratory to continue his work. That, of course, is when Bisco inexplicably shows up behind him, and the episode ends there, with our two leads meeting face to face for the first time.

A lot about Sabikui Bisco reminds one of Dorohedoro, but beyond that I struggle for reference points. (And even in that context, Bisco is very much its own thing.) This is absolutely one to keep an eye on, we might be looking at the start of something big. Even if not, it promises to be intriguing.

Grade: A-
The Takeaway: If you have the time, give the first episode of this a watch. It’s interesting.

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